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Drugs that have been shown to improve outcomes for patients with HF with reduced ejection fraction generally also lower BP.
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Long-term consequences of the diabetic state include macrovascular complications (premature or accelerated atherosclerosis with resulting coronary, cerebral, and peripheral vascular insufficiency) and microvascular complications (retinopathy, nephropathy, and neuropathy).
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Unblinded data were made available exclusively to the independent data safety and monitoring board by a statistician who was independent of the trial.
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Based on the results of the above studies, this study was designed to investigate the following in individuals with high-normal blood pressure: whether intervening with telmisartan and indapamide can strikingly alter the metabolic risk factors; what pharmacodynamic differences exist between them, particularly in individuals with abdominal obesity; and the pharmacoeconomics of these two drugs.
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It is important to tell your doctor if you have any other medical conditions, especially if you suffer from any of the following: angina; heart attack, heart failure or other cardiac problems; dehydration; hyponatremia; kidney disease; and liver disease.
The duration of follow-up for most studies was between 8 and 12 weeks.
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